Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy

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منابع مشابه

Hypothermia in neonatal hypoxic-ischemic encephalopathy (HIE).

Neonatal hypoxic-ischemic encephalopathy (HIE) significantly affects neurodevelopment in infants and is also considered as an important cause of neonatal deaths worldwide. Medical research is being focused worldwide for the development of therapeutic avenues but it is still managed by supportive care. The latest studies in the above field have shown the efficacy of prolonged cooling of neonate'...

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Systemic hypothermia--a "cool" therapy for neonatal hypoxic-ischemic encephalopathy.

Hypoxic–ischemic encephalopathy is an important cause of death and disability in full-term infants. The incidence of moderate or severe hypoxic– ischemic encephalopathy has remained essentially unchanged over the past 20 years, at 1.5 to 2 per 1000 live births in the United States. Approximately 15 to 20 percent of these infants will die, and 20 to 25 percent of those who survive will be disabl...

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Emerging Use of Therapeutic Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy

Objective: Several clinical trials evaluating the efficacy of hypothermia in neonates with encephalopathy have shown significant reduction in death and disability at 18-month follow-up. We sought to: 1) evaluate how the use of hypothermia for neonatal hypoxic ischemic encephalopathy (HIE) is changing in U.S. clinical practice, 2) determine which methods and devices for delivering hypothermia ar...

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Neonatal seizures and therapeutic hypothermia for hypoxic-ischemic encephalopathy.

Neonatal seizures are associated with morbidity and mortality. Hypoxic-ischemic encephalopathy (HIE) is the most common cause of seizures in newborns. Neonatal animal models suggest that therapeutic hypothermia can reduce seizures and epileptiform activity in the setting of hypoxia-ischemia, however data from human studies have conflicting results. In this research highlight, we will discuss th...

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Hypothermia: a neuroprotective therapy for neonatal hypoxic-ischemic encephalopathy.

t he incidence of hypoxic ischemic encephalopathy in the United States is 2.8/1000 live births of which 10–15% of the infants succumb and 25–30% suffer permanent neurologic damage: mental retardation, cerebral palsy and epilepsy. The incidence is tenfold higher in the developing world [1-3]. Experimental evidence has confirmed that HIE is an evolving process lasting hours to weeks. Understandin...

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ژورنال

عنوان ژورنال: Archives of Pediatrics & Adolescent Medicine

سال: 2012

ISSN: 1072-4710

DOI: 10.1001/archpediatrics.2011.1772